About the Study

The University of Oxford is the lead centre for the study, and the day to day running of the study is being completed by Oxford Trauma, a research group of the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences.

Current enrolment curve

Recruitment target: 344

Current Expected : 344

Current Actual : 377

Information about the Study


The AFTER Study is trying to find out if attending physiotherapy after an ankle fracture really does help improve recovery.

Study Funder

The study is funded by the Department of Health (National Institute for Health and Care Research – Research for Patient Benefit (NIHR201950)) and is the work of Physiotherapists across the UK, with research support from The University of Oxford.

Study Sponsor

The University of Oxford is the lead centre and sponsor for this study.

Study Design

AFTER is a multi-centre, parallel-group, superiority individually randomised controlled study assessing the clinical effectiveness of supervised versus self-directed rehabilitation in improving ankle function for people aged 50 years and over after an ankle fracture. The study will be conducted at secondary care trauma departments in a minimum of 20 NHS hospitals and their related physiotherapy services.

Personal Data

Personal details will be held by the research team at the University of Oxford. All information that is collected during the course of the research will be used and stored in accordance with the current data protection legislation.

Things to Know

There is currently no scientific evidence showing that seeing a physiotherapist after an ankle fracture improves recovery.

Study team

The research team for the AFTER Study has a lot of experience in caring for patients with fracture injuries and are active in health research. Members of the public have also been involved in the development of this study, and are involved in the management.

david keene

David Keene

Specialist Orthopaedic Physiotherapist and Extended Scope Practitioner at the Royal United Hospital in Bath

Dr Keene is the Chief Investigator for this study.

Kylea Draper

Clinical Trial Manager

Kylea is a trial manager who has worked in orthopaedic trials for the last four years. She oversees the day to day running of the AFTER trial.

Hannah Crook

Study Administrator

Hannah is a study administrator who works across multiple orthopaedic trials within NDORMS portfolio

Interactive map of the locations where the AFTER study is taking place

  • Doncaster & Bassetlaw Teaching Hospitals NHS Foundation Trust
  • John Radcliffe Hospital
  • King's College Hospital
  • Musgrove Park
  • Nottingham University Hospitals
  • Pinderfields Hospital
  • Princess Alexandra Hospital
  • Royal United Hospitals Bath
  • Southmead Hospital
  • Ysbyty Gwynedd
  • Airedale NHS Foundation Trust
  • East Sussex Healthcare NHS Trust
  • Hampshire Hospitals NHS Foundation Trust
  • Leicester Royal Infirmary
  • Luton and Dunstable
  • Milton Keynes Hospital
  • NHS Fife
  • North West Anglia
  • Northumbria Healthcare NHS Trust
  • Nottingham University Hospitals
  • Royal Devon University Healthcare NHS Foundation Trust
  • Sheffield Teaching Hospitals NHS Foundation Trust
  • South Tyneside and Sunderland NHS FT
  • Southmead Hospital
  • Surrey and Sussex Healthcare NHS Trust (East Surrey)
  • William Harvey Hospital
  • Royal Cornwall Hospital
  • West Suffolk Hospital